Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.55 |
| ▸ | NT5E | P21589 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.51 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.51 |
| ▸ | P4HTM | Q9NXG6 | 3/20 | 0.51 |
| ▸ | PRKCG | P05129 | 2/20 | 0.51 |
| ▸ | GLI1 | P08151 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14682826 | 1.00 | GPBAR1 (0.55) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL18124336 | 0.95 | GPBAR1 (0.61) | GPBAR1NT5ELMNASMN1; SMN2PRKCG | |
| SCHEMBL17162701 | 0.95 | GPBAR1 (0.61) | GPBAR1NT5ELMNASMN1; SMN2PRKCG | |
| SCHEMBL9888542 | 0.93 | GPBAR1 (0.53) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL9105293 | 0.93 | GPBAR1 (0.53) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL9888468 | 0.92 | GPBAR1 (0.52) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL15185806 | 0.91 | GPBAR1 (0.51) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL14682801 | 0.90 | GPBAR1 (0.56) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL15185742 | 0.89 | PTGES (0.52) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 | |
| SCHEMBL9889521 | 0.89 | GPBAR1 (0.49) | GPBAR1NT5ELMNASMN1; SMN2EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142653-A1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142653-A1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | ERG28, BET1, BRD3 | GPBAR1 2177/4885NT5E 3212/4885LMNA 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.