Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.37 |
| ▸ | ACHE | P22303 | 7/20 | 0.37 |
| ▸ | BCHE | P06276 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7926083 | 0.78 | AOC3 (0.44) | PTGS2ACHEBCHEFFAR1ALDH1A1 | |
| SCHEMBL3871619 | 0.77 | CYP3A4 (0.48) | PTGS2ACHEBCHENPC1RAB9A | |
| SCHEMBL6204158 | 0.77 | AOC3 (0.45) | ACHEFFAR1 | |
| SCHEMBL8309641 | 0.77 | PTGS2 (0.37) | PTGS2ACHEBCHE | |
| SCHEMBL31175995 | 0.77 | IDO1 (0.43) | PTGS2ACHEBCHEALDH1A1 | |
| SCHEMBL3141582 | 0.77 | IDO1 (0.43) | PTGS2ACHEBCHEALDH1A1 | |
| SCHEMBL6155751 | 0.77 | AOC3 (0.45) | FFAR1MEN1KMT2A | |
| SCHEMBL5377867 | 0.77 | HIF1A (0.49) | PTGS2ACHEBCHELMNARAB9A | |
| SCHEMBL27830263 | 0.76 | MEN1 (0.41) | PTGS2ACHEBCHELMNAMEN1 | |
| Bromide SCHEMBL28174072 | 0.76 | PTGS2 (0.36) | PTGS2ACHEBCHEL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142915-A1 | CYCLOPROPYL MIDA BORONATE | MIDCAP FINANCIAL TRUST | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142915-A1 | CYCLOPROPYL MIDA BORONATE | MB, MMAB, MDK | PTGS2 3980/4885ACHE 4294/4885BCHE 639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.