SCHEMBL98917

SCHEMBL98917

O=[C]OCc1ccccc1Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.55
PNMT P11086 2/20 0.45
NR4A2 P43354 2/20 0.45
MAOB P27338 2/20 0.44
MAOA P21397 1/20 0.44
TAAR1 Q96RJ0 1/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
FABP4 P15090 1/20 0.41
FABP5 Q01469 1/20 0.41
CASP3 P42574 1/20 0.41
SENP8 Q96LD8 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
MMP1 P03956 1/20 0.41
MMP2 P08253 1/20 0.41
MMP9 P14780 1/20 0.41
MMP12 P39900 1/20 0.41
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1683184 0.86 IDO1 (0.60) IDO1PNMTTAAR1SMN1; SMN2
SCHEMBL10639801 0.81 IDO1 (0.57) IDO1PNMTNR4A2MAOBMAOA
SCHEMBL10389103 0.80 IDO1 (0.52) IDO1PNMTNR4A2MAOBMAOA
SCHEMBL2094946 0.80 TAAR1 (0.48) IDO1PNMTTAAR1NPC1RAB9A
SCHEMBL331882 0.77 SMN1; SMN2 (0.44) IDO1TAAR1L3MBTL1HPGDSMN1; SMN2
SCHEMBL5984175 0.77 GABRA1 (0.41) IDO1L3MBTL1HPGD
SCHEMBL6943180 0.76 IDO1 (0.40) IDO1NR4A2MAOBHPGDSMN1; SMN2
SCHEMBL9808663 0.76 IDO1 (0.52) IDO1PNMTNR4A2MAOBMAOA
SCHEMBL47974 0.76 IDO1 (0.58) IDO1NR4A2L3MBTL1FABP4FABP5
SCHEMBL177343 0.75 FDPS (0.38) IDO1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8313 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3717452-B1 PROCESS FOR PREPARING ACYLATED AMPHETAMINE DERIVATIVES SpecGx LLC (US) 2024-06-05 EP claimed
CN-117659119-A RGD fragment, method for preparing polypeptide by utilizing RGD fragment and application of RGD fragment 珠海市藤栢医药有限公司 2024-03-08 CN claimed
US-11779653-B2 Multi-armed polyrotaxane platform for protected nucleic acid delivery THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-10 US claimed
EP-3565573-B1 PAC1 RECEPTOR AGONISTS (MAXCAPS) AND USES THEREOF UNIV CALIFORNIA (US) 2023-08-23 EP claimed
WO-2023151188-A1 GREEN SYNTHESIS METHOD OF ANTIVIRAL DRUG INTERMEDIATE 上海皓元医药股份有限公司 2023-08-17 WO claimed
US-11713340-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-08-01 US claimed
US-11673957-B2 Anti-ROR2 antibodies Eureka Therapeutics, Inc. (US) 2023-06-13 US claimed
US-11603369-B2 Divalent nucleobase compounds and uses therefor CARNEGIE MELLON UNIVERSITY (US) 2023-03-14 US claimed
EP-4140988-A1 L-VALINATE OF HYDROXYPROPYLTHIAZOLIDINE CARBOXAMIDE DERIVATIVE AND SALT FORM, CRYSTAL POLYMORPH THEREOF Merck Serono S.A. (CH) 2023-03-01 EP claimed
US-11555055-B2 Peptide inhibitors of insulin-degrading enzyme THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-01-17 US claimed
US-4011182-A HORMONE INHIBITOR; SOMATOTROPIN AMERICAN HOME PRODUCTS CORPORATION (US) 1977-03-08 US claimed
US-4000259-A DIABETES AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-28 US claimed
US-3998795-A (Acyl-D-α-amino acid-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-21 US claimed
US-3997517-A PEPTIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1976-12-14 US claimed
US-3991041-A GROWTH HORMONE RELEASE INHIBITOR AMERICAN HOME PRODUCTS CORPORATION (US) 1976-11-09 US claimed
US-3988308-A (Tyr3, Tyr14)-SRIF and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-26 US claimed
US-3988304-A Cyclic dodecapeptide derivatives of somatostatin and intermediates thereof AMERICAN HOME PRODUCTS CORPORATION (US) 1976-10-26 US claimed
US-3937695-A P-Glu-Trp-Ser-Tyr-D-Lys-Leu-Arg-Pro-Gly-NH2 and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-02-10 US claimed
US-3933784-A Des-(ser13)-srif and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 US claimed
US-3931140-A (H-gly-gly-tyr-ala)1 -somatostatin AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US claimed