Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
| ▸ | BCHE | P06276 | 3/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 5/20 | 0.41 |
| ▸ | NMT2 | O60551 | 4/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24276406 | 0.98 | SIGMAR1 (0.57) | SIGMAR1BCHEEPHX1NPC1RAB9A | |
| SCHEMBL11090 | 0.90 | SIGMAR1 (0.49) | SIGMAR1BCHEEPHX1NPC1RAB9A | |
| SCHEMBL28580462 | 0.89 | BCHE (0.51) | SIGMAR1BCHEEPHX1RENNMT1 | |
| SCHEMBL942700 | 0.86 | SIGMAR1 (0.57) | SIGMAR1BCHEEPHX1NPC1RAB9A | |
| SCHEMBL12413657 | 0.82 | SIGMAR1 (0.57) | SIGMAR1BCHEEPHX1NQO2MTNR1A | |
| SCHEMBL9891910 | 0.82 | SIGMAR1 (0.43) | SIGMAR1BCHEEPHX1DPP4PREP | |
| SCHEMBL19652274 | 0.81 | EPHX1 (0.55) | EPHX1NPC1RAB9AL3MBTL1DPP4 | |
| SCHEMBL13581 | 0.81 | EPHX1 (0.55) | EPHX1NPC1RAB9AL3MBTL1DPP4 | |
| SCHEMBL14503312 | 0.80 | EPHX1 (0.62) | SIGMAR1BCHEEPHX1NPC1RAB9A | |
| SCHEMBL12026402 | 0.79 | EPHX1 (0.52) | EPHX1NPC1RAB9AL3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | SIGMAR1 212/4885BCHE 3324/4885EPHX1 1834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.