Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9891831 | 0.87 | SORD (0.46) | — | |
| SCHEMBL9893154 | 0.85 | ACACB (0.45) | ACACBMTORPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9893036 | 0.83 | ACACB (0.44) | ACACBMTORPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL9892342 | 0.82 | ACACB (0.48) | ACACBMTORPIK3CAPIK3CD | |
| SCHEMBL3702197 | 0.80 | ACACB (0.46) | ACACBMTORPIK3CAMGLLCHRNA7 | |
| SCHEMBL9891829 | 0.75 | HRH4 (0.37) | — | |
| SCHEMBL2569083 | 0.74 | CNR2 (0.47) | — | |
| SCHEMBL5485306 | 0.74 | PIK3CA (0.49) | ACACBMTORPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL5457199 | 0.72 | PIK3CA (0.55) | ACACBMTORPIK3CAPIK3CDPIK3R1 | |
| SCHEMBL16480420 | 0.71 | SORD (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | ACACB 1735/4885MTOR 2112/4885PIK3CA 1165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.