Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.58 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.57 |
| ▸ | TYR | P14679 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 1/20 | 0.57 |
| ▸ | CDC25B | P30305 | 1/20 | 0.57 |
| ▸ | CDC25C | P30307 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | PRKACA | P17612 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28584177 | 0.87 | ALOX5 (0.69) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL9891792 | 0.86 | ABL1 (0.72) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL2752589 | 0.86 | LMNA (0.68) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL4787902 | 0.84 | ABL1 (0.74) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL10922743 | 0.84 | KMT2A (0.70) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL10809273 | 0.84 | LMNA (0.82) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL13015623 | 0.81 | KMT2A (0.62) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL14085826 | 0.81 | KMT2A (0.74) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL3178473 | 0.81 | KMT2A (0.62) | LMNAKMT2AMEN1RAB9AMAPK1 | |
| SCHEMBL29276744 | 0.80 | KMT2A (0.58) | LMNAKMT2AMEN1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | LMNA 4696/4885KMT2A 3551/4885MEN1 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.