SCHEMBL9892485

SCHEMBL9892485

CN(C)/C=C/C=C(C#N)C#N

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 0.42
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
SNCA P37840 1/20 0.31
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10922299 1.00 APP (0.42) APPKMT2AMEN1ALDH1A1MAPT
SCHEMBL28272902 0.78
SCHEMBL24345060 0.76 TDP1 (0.31)
SCHEMBL24344751 0.76 TDP1 (0.31)
SCHEMBL29036670 0.76 TDP1 (0.31)
SCHEMBL12758231 0.75 APP (0.35) APPKMT2AMEN1ALDH1A1MAPT
SCHEMBL14254900 0.73 DNM1 (0.36) APPKMT2AMEN1ALDH1A1MAPT
SCHEMBL12864668 0.73 DNM1 (0.36) APPKMT2AMEN1ALDH1A1MAPT
SCHEMBL3189804 0.73 APP (0.35) APPKMT2AMEN1MAPT
Dimethylamine SCHEMBL28572090 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2704683-B1 CHROMOPHORES WITH PERFLUOROALKYL SUBSTITUENTS BASF SE (DE) 2017-10-18 EP disclosed
US-8829192-B2 Stabilization of body-care and household products against degradation by uv radiation using merocyanine derivatives BASF SE (DE) 2014-09-09 US disclosed
US-20120140161-A1 POLYMER FILM, RETARDATION FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND ULTRAVIOLET ABSORBER FUJIFILM CORPORATION (JP) 2012-06-07 US disclosed
US-20110229662-A1 Polymer film, production method for the film, and retardation film, polarizing plate and liquid-crystal display device having the film FUJIFILM CORPORATION (JP) 2011-09-22 US disclosed
US-20090264657-A1 Stabilization of body-care and household products against degradation by uv radiation using merocyanine derivatives CIBA CORPORATION 2009-10-22 US disclosed
US-20090130033-A1 Dendrimer-Aminobuadiene-Based Uv Screens FUJI PHOTO FILM B.V. (NL) 2009-05-21 US disclosed
US-20080260661-A1 Aminobutadiene-Based Uv Screens FUJI PHOTO FILM B.V. 2008-10-23 US disclosed
EP-0057827-B1 PROCESS FOR THE PREPARATION OF 2-AMINOPYRIDINE DERIVATIVES BASF Aktiengesellschaft (DE) 1986-08-13 EP disclosed
EP-0057363-B1 PROCESS FOR PREPARING BUTADIENEDINITRILES BASF Aktiengesellschaft (DE) 1984-09-12 EP disclosed
US-4410465-A Preparation of butadiene dinitriles BASF AKTIENGESELLSCHAFT (DE) 1983-10-18 US disclosed
US-4395555-A Preparation of 2-aminopyridine derivatives BASF AKTIENGESELLSCHAFT (DE) 1983-07-26 US disclosed
EP-0057363-A1 Process for preparing butadienedinitriles BASF Aktiengesellschaft (DE) 1982-08-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264657-A1 Stabilization of body-care and household products against degradation by uv radiation using merocyanine derivatives ERCC5, XRCC6, XRCC5 APP 648/4885KMT2A 2802/4885MEN1 134/4885
US-20080260661-A1 Aminobutadiene-Based Uv Screens ALAD, AAAS, ALDH7A1 APP 489/4885KMT2A 2884/4885MEN1 1641/4885
US-20090130033-A1 Dendrimer-Aminobuadiene-Based Uv Screens UROD, AAAS, ALAD APP 1189/4885KMT2A 1731/4885MEN1 959/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.