Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2417762 | 0.98 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CHTR1DCYP1A2 | |
| SCHEMBL10948416 | 0.92 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL6292172 | 0.92 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL2516256 | 0.92 | ADRA2A (0.38) | ADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL6660516 | 0.87 | HTR1D (0.40) | ADRA2AADRA2BADRA2CHTR1D | |
| SCHEMBL9398117 | 0.83 | FAAH (0.42) | — | |
| SCHEMBL9398124 | 0.83 | FAAH (0.42) | — | |
| SCHEMBL20052856 | 0.82 | — | — | |
| SCHEMBL7267539 | 0.80 | — | — | |
| SCHEMBL10619672 | 0.78 | MIF (0.33) | ADRA2AADRA2BADRA2CHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2275100-A2 | Compounds with anti-parasitic activity and drugs containing said compounds | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-01-19 | — | — | EP | disclosed |
| EP-2266555-A2 | Compounds with antiparasitic activity and medicines containing same | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-12-29 | — | — | EP | disclosed |
| EP-2260840-A2 | Compounds with antiparasitic activity and medicines containing same | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260841-A2 | Compounds with antiparasitic activity and medicines containing same | Centre National de la Recherche Scientifique (CNRS) (FR) | 2010-12-15 | — | — | EP | disclosed |
| EP-1524972-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY AND MEDICINES CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004009068-A2 | COMPOUNDS WITH ANTIPARASITIC ACTIVITY AND MEDICINES CONTAINING SAME | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2004-01-29 | — | — | WO | disclosed |