SCHEMBL989270

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL990022	0.94	OPRM1 (0.81)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL8804	0.90	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL916599	0.90	OPRM1 (1.00)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL4321837	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL4324385	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL4971300	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL22637301	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL28383546	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL18249370	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2
	Fentanyl SCHEMBL4326756	0.89	OPRM1 (0.98)	OPRM1OPRD1OPRK1SLC22A1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.