Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12698329 | 0.91 | NR1H4 (0.46) | GPBAR1PRKCD | |
| SCHEMBL9891336 | 0.88 | GPBAR1 (0.57) | GPBAR1PRKCD | |
| SCHEMBL9892728 | 0.88 | NR1H4 (0.48) | GPBAR1 | |
| SCHEMBL9110970 | 0.88 | GPBAR1 (0.53) | GPBAR1PRKCD | |
| SCHEMBL9891265 | 0.87 | GPBAR1 (0.56) | GPBAR1PRKCD | |
| SCHEMBL19129752 | 0.84 | NR1H4 (0.46) | GPBAR1PRKCD | |
| SCHEMBL15947454 | 0.83 | NR1H4 (0.50) | GPBAR1 | |
| SCHEMBL9108376 | 0.83 | NR1H4 (0.50) | GPBAR1 | |
| SCHEMBL12698224 | 0.83 | — | — | |
| SCHEMBL12698314 | 0.82 | GPBAR1 (0.63) | GPBAR1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142653-A1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142653-A1 | C-28 AMIDES OF MODIFIED C-3 BETULINIC ACID DERIVATIVES AS HIV MATURATION INHIBITORS | ERG28, BET1, BRD3 | GPBAR1 2177/4885PRKCD 2347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.