Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23501578 | 0.87 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL990048 | 0.86 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL991387 | 0.80 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL620057 | 0.80 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL30912786 | 0.76 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL5581611 | 0.74 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL4167430 | 0.73 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL11032545 | 0.73 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2TDP1TSHRMAPK1 | |
| SCHEMBL990916 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL31229222 | 0.72 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096713-B2 | Method for the phosphine-initialized production of hyperbranched polyols | BASF SE (DE) | 2015-08-04 | — | — | US | disclosed |
| EP-2448994-B1 | METHOD FOR THE PHOSPHINE-INITIALIZED PRODUCTION OF HYPERBRANCHED POLYOLS | BASF SE (DE) | 2013-08-14 | — | — | EP | disclosed |
| EP-2448994-A1 | METHOD FOR THE PHOSPHINE-INITIALIZED PRODUCTION OF HYPERBRANCHED POLYOLS | BASF SE (DE) | 2012-05-09 | — | — | EP | disclosed |
| US-20120101308-A1 | METHOD FOR THE PHOSPHINE-INITIALIZED PRODUCTION OF HYPERBRANCHED POLYOLS | BASF SE (DE) | 2012-04-26 | — | — | US | disclosed |
| WO-2011000854-A1 | METHOD FOR THE PHOSPHINE-INITIALIZED PRODUCTION OF HYPERBRANCHED POLYOLS | BASF SE (DE) | 2011-01-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101308-A1 | METHOD FOR THE PHOSPHINE-INITIALIZED PRODUCTION OF HYPERBRANCHED POLYOLS | PHOSPHO1, PPIP5K2, SELENOI | ALDH1A1 2675/4885SMN1; SMN2 3374/4885TDP1 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.