Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.64 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | WNT3A | P56704 | 1/20 | 0.64 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28579111 | 0.88 | MAPT (0.59) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL14085826 | 0.85 | KMT2A (0.74) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL16254980 | 0.85 | ABL1 (0.79) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL21505853 | 0.83 | RAB9A (0.58) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL14085829 | 0.83 | MAPT (0.75) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL24026399 | 0.82 | RAB9A (0.74) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL9891517 | 0.82 | RAB9A (0.64) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL14085825 | 0.81 | HDAC1 (0.67) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL8402291 | 0.80 | MAPT (0.73) | MEN1KMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL22500616 | 0.80 | GSTO1 (0.66) | MEN1KMT2ARAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383615-B2 | Azetidine 2-carboxamide derivatives which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20120142666-A1 | Azetidine 2-Carboxamide Derivatives Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142666-A1 | Azetidine 2-Carboxamide Derivatives Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | MEN1 4667/4885KMT2A 1863/4885RAB9A 1317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.