Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 7/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.46 |
| ▸ | PLK1 | P53350 | 5/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893047 | 0.85 | MEN1 (0.54) | PTGER2HDAC8HDAC6MAP4K1MEN1 | |
| SCHEMBL16480487 | 0.82 | HDAC2 (0.46) | PLK1HDAC2HDAC8HDAC6MEN1 | |
| SCHEMBL9103589 | 0.81 | PHGDH (0.47) | PTGER2PTGER3HDAC2HDAC8HDAC6 | |
| SCHEMBL9103598 | 0.81 | PHGDH (0.47) | PTGER2PTGER3HDAC2HDAC8HDAC6 | |
| SCHEMBL9892976 | 0.80 | PTGER2 (0.41) | PTGER2PTGER3PTGER4PTGDRMAP4K1 | |
| SCHEMBL16542445 | 0.78 | HDAC2 (0.42) | PLK1HDAC2HDAC8HDAC6MEN1 | |
| SCHEMBL9891740 | 0.78 | HDAC6 (0.42) | PTGER2PTGER3HDAC2HDAC8HDAC6 | |
| SCHEMBL9893023 | 0.77 | PER2 (0.46) | PTGER2PTGER3PTGDRMAP4K1MEN1 | |
| SCHEMBL9893157 | 0.77 | PTGER2 (0.42) | PTGER2PTGER3PTGER4PTGDRMAP4K1 | |
| SCHEMBL6789962 | 0.77 | PTGER2 (0.49) | PTGER2PTGER3PTGER4PTGDRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | PTGER2 186/4885PTGER3 200/4885PLK1 2361/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.