Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13285331 | 0.86 | ALDH1A1 (0.42) | ALDH1A1KDM4EALOX15KMT2AHSD17B10 | |
| SCHEMBL9892995 | 0.83 | CNR1 (0.50) | ALDH1A1KDM4EKMT2AMAPTHPGD | |
| SCHEMBL16480386 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EALOX15KMT2AHSD17B10 | |
| SCHEMBL9891889 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KDM4EALOX15KMT2AHSD17B10 | |
| SCHEMBL9893169 | 0.75 | FFAR1 (0.46) | ALDH1A1KDM4ECHRNB1CHRNB2CHRNB4 | |
| SCHEMBL9107822 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1KDM4EALOX15KMT2AHSD17B10 | |
| SCHEMBL9107827 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1KDM4EALOX15KMT2AHSD17B10 | |
| SCHEMBL28220645 | 0.71 | AR (0.45) | ALDH1A1KMT2AMEN1TSHRNR1I2 | |
| SCHEMBL25693763 | 0.70 | HTT (0.50) | ALDH1A1MAPTHPGDNR1I2SMARCA2 | |
| SCHEMBL9893131 | 0.70 | AR (0.43) | ALDH1A1MAPTHPGDCHRNB1CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142677-A1 | Pyrrolidine Compounds Which Modulate The CB2 Receptor | CNR2, CNR1, OPRL1 | ALDH1A1 3279/4885KDM4E 2527/4885ALOX15 966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.