Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.51 |
| ▸ | TK1 | P04183 | 3/20 | 0.44 |
| ▸ | NT5M | Q9NPB1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TYMP | P19971 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9893552 | 1.00 | RNASE1 (0.51) | RNASE1TK1NT5MALDH1A1HTT | |
| SCHEMBL26806629 | 0.90 | RNASE1 (0.54) | RNASE1TK1NT5MALDH1A1TYMP | |
| SCHEMBL26288067 | 0.89 | RNASE1 (0.48) | RNASE1TK1NT5MALDH1A1HTT | |
| SCHEMBL9893412 | 0.86 | POLB (0.40) | RNASE1POLB | |
| SCHEMBL9893411 | 0.86 | POLB (0.40) | RNASE1POLB | |
| SCHEMBL25401527 | 0.84 | RNASE1 (0.44) | RNASE1TK1NT5MALDH1A1HTT | |
| SCHEMBL25401520 | 0.84 | RNASE1 (0.44) | RNASE1TK1NT5MALDH1A1HTT | |
| SCHEMBL1277770 | 0.80 | RNASE1 (0.49) | RNASE1TK1NT5MALDH1A1HTT | |
| SCHEMBL25400227 | 0.78 | RNASE1 (0.47) | RNASE1TK1NT5MTYMPLMNA | |
| SCHEMBL25400232 | 0.78 | RNASE1 (0.47) | RNASE1TK1NT5MTYMPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (AL) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149657-A1 | 2'-FLUORO ARABINO NUCLEOSIDES AND USE THEREOF | SLC29A2, DUT, SLC29A1 | RNASE1 88/4885TK1 123/4885NT5M 254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.