Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL28085429 | 1.00 | DAO (0.41) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28094912 | 0.91 | DAO (0.44) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL505771 | 0.89 | TSHR (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL235922 | 0.89 | TSHR (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL11436196 | 0.89 | TSHR (0.52) | DAOTSHRNAPRTCES2CES1 | |
| Methacrylic Acid SCHEMBL1356993 | 0.84 | TGFBR1 (0.37) | LMNAALDH1A1 | |
| Methacrylic Acid SCHEMBL443710 | 0.84 | TGFBR1 (0.37) | LMNAALDH1A1 | |
| Methacrylic Acid SCHEMBL2223377 | 0.84 | TGFBR1 (0.37) | LMNAALDH1A1 | |
| Methacrylic Acid SCHEMBL20873324 | 0.84 | TGFBR1 (0.37) | LMNAALDH1A1 | |
| Methacrylic Acid SCHEMBL28225727 | 0.84 | TGFBR1 (0.37) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8708475-B2 | Ultraviolet crosslinking inkjet ink, ink cartridge containing same, and image forming method and apparatus using same | RICOH COMPANY, LTD. (JP) | 2014-04-29 | — | — | US | disclosed |
| US-20120147103-A1 | ULTRAVIOLET CROSSLINKING INKJET INK, INK CARTRIDGE CONTAINING SAME, AND IMAGE FORMING METHOD AND APPARATUS USING SAME | RICOH COMPANY, LTD. (JP) | 2012-06-14 | — | — | US | disclosed |