Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL11436196 | 1.00 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL235922 | 1.00 | TSHR (0.52) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2160785 | 0.93 | TSHR (0.45) | TSHRDAONAPRTCES1CES2 | |
| Terephthalic Acid SCHEMBL28441196 | 0.92 | TSHR (0.48) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL890408 | 0.91 | TSHR (0.42) | TSHRDAONAPRTCES1CES2 | |
| Isophthalic Acid SCHEMBL11853911 | 0.89 | CA12 (0.44) | TP53HPGDCYP2C9KMO | |
| Benzoic Acid SCHEMBL9894638 | 0.89 | DAO (0.41) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL28085429 | 0.89 | DAO (0.41) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL11508647 | 0.89 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 | |
| Benzoic Acid SCHEMBL2020361 | 0.89 | TSHR (0.56) | TSHRDAONAPRTCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656818-B | metal oxide dispersion | 凯斯科技股份有限公司 | 2023-11-17 | — | — | CN | claimed |
| CN-114656818-A | Metal oxide dispersion | 凯斯科技股份有限公司 | 2022-06-24 | — | — | CN | claimed |
| US-11319390-B2 | Poly(ethylene glycol) methacrylate microgels, preparation method and uses | LVMH RECHERCHE (FR) | 2022-05-03 | — | — | US | claimed |
| US-20200377674-A1 | POLY(ETHYLENE GLYCOL) METHACRYLATE MICROGELS, PREPARATION METHOD AND USES | LVMH RECH (FR) | 2020-12-03 | — | — | US | claimed |
| US-10799610-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2020-10-13 | — | — | US | claimed |
| US-10413632-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2019-09-17 | — | — | US | claimed |
| US-20180264165-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2018-09-20 | — | — | US | claimed |
| US-9993576-B2 | Cement products and methods of making and using the same | PIONEER SURGICAL TECHNOLOGY, INC. (US) | 2018-06-12 | — | — | US | claimed |
| EP-2192886-B1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | PIONEER SURGICAL TECH INC (US) | 2017-12-20 | — | — | EP | claimed |
| US-20170333594-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | MIDCAP FINANCIAL TRUST | 2017-11-23 | — | — | US | claimed |
| EP-1675943-A4 | NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2007-12-05 | — | — | EP | claimed |
| US-7262230-B2 | Process of preparing crosslinked, low loss polymers with tunable refractive indices | LUMERA CORPORATION (US) | 2007-08-28 | — | — | US | claimed |
| US-20060167213-A1 | Process of preparing crosslinked, low loss polymers with tunable refractive indices | SILICON VALLEY BANK | 2006-07-27 | — | — | US | claimed |
| EP-1675943-A2 | NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF | Massachusetts Institute of Technology (US) | 2006-07-05 | — | — | EP | claimed |
| EP-1539344-A2 | PRODUCTION OF POLYMERIC MICROARRAYS | Massachusetts Institute Of Technology (US) | 2005-06-15 | — | — | EP | claimed |
| WO-2005028619-A2 | NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2005-03-31 | — | — | WO | claimed |
| US-20050019747-A1 | Nanoliter-scale synthesis of arrayed biomaterials and screening thereof | NATIONAL INSTITUTES OF HEALTH | 2005-01-27 | — | — | US | claimed |
| WO-2004043588-A2 | PRODUCTION OF POLYMERIC MICROARRAYS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2004-05-27 | — | — | WO | claimed |
| US-20040028804-A1 | Production of polymeric microarrays | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-02-12 | — | — | US | claimed |
| US-4218355-A | Low organic solvent-containing polyester coating compositions | PPG INDUSTRIES, INC. (US) | 1980-08-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180264165-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | BHMT2, SHMT1, BHMT | TSHR 4435/4885DAO 194/4885NAPRT 1765/4885 |
| US-20170333594-A1 | CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME | BHMT2, SHMT1, BHMT | TSHR 4435/4885DAO 194/4885NAPRT 1765/4885 |
| US-10799610-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | TSHR 4435/4885DAO 194/4885NAPRT 1765/4885 |
| US-10413632-B2 | Cement products and methods of making and using the same | BHMT2, SHMT1, BHMT | TSHR 4435/4885DAO 194/4885NAPRT 1765/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.