SCHEMBL9894849

SCHEMBL9894849

Cc1cc(C)nc(N(C)C)c1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
TSHR P16473 1/20 0.47
NOS3 P29474 2/20 0.46
NOS2 P35228 2/20 0.46
NOS1 P29475 1/20 0.46
TAAR1 Q96RJ0 1/20 0.43
DNM2 P50570 1/20 0.40
NUDT1 P36639 1/20 0.36
KCNH2 Q12809 1/20 0.34
SLC2A1 P11166 1/20 0.34
POLB P06746 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
ENPP1 P22413 1/20 0.33
UHRF1 Q96T88 1/20 0.32
MCHR1 Q99705 1/20 0.31
NCF1 P14598 1/20 0.31
MDM2 Q00987 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12250747 0.78 NOS3 (0.40) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL12250731 0.78 NOS2 (0.40) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL16941548 0.78 NOS3 (0.40) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL30336057 0.76 MEN1 (1.00) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL9977693 0.76 KMT2A (0.57) MEN1KMT2ATSHRTAAR1DNM2
SCHEMBL6463426 0.76 KMT2A (0.57) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL432253 0.76 MEN1 (1.00) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL4925827 0.76 MEN1 (0.52) MEN1KMT2ATSHRNOS3NOS2
SCHEMBL2757263 0.75 KMT2A (0.61) MEN1KMT2ATSHRTAAR1DNM2
SCHEMBL12250813 0.75 KMT2A (0.44) MEN1KMT2ANOS3NOS2NOS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3211123-B1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS ROHM & HAAS ELECT MAT (US) 2019-01-09 EP claimed
US-20170251557-A1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS ROHM & HAAS ELECT MAT (US) 2017-08-31 US claimed
EP-3211123-A1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS Rohm and Haas Electronic Materials LLC (US) 2017-08-30 EP claimed
CN-102605356-B Plating catalyst and method ROHM & HAAS ELECT MAT 2014-11-19 CN claimed
US-8591636-B2 Plating catalyst and method ROHM AND HAAS ELECTRONICS MATERIALS LLC (US) 2013-11-26 US claimed
CN-107130230-B The horizontal process of the electroless metal plating of substrate with ionic catalyst 罗门哈斯电子材料有限责任公司 2019-08-27 CN disclosed
EP-3211123-B1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS ROHM & HAAS ELECT MAT (US) 2019-01-09 EP disclosed
EP-2465974-B1 Plating catalyst and method ROHM & HAAS ELECT MAT (US) 2018-11-28 EP disclosed
CN-107130230-A The horizontal process of the electroless metal plating of substrate with ionic catalyst 罗门哈斯电子材料有限责任公司 2017-09-05 CN disclosed
US-20170251557-A1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS ROHM & HAAS ELECT MAT (US) 2017-08-31 US disclosed
EP-3211123-A1 HORIZONTAL METHOD OF ELECTROLESS METAL PLATING OF SUBSTRATES WITH IONIC CATALYSTS Rohm and Haas Electronic Materials LLC (US) 2017-08-30 EP disclosed
US-8961669-B2 Plating catalyst and method ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2015-02-24 US disclosed
EP-2195311-B1 PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS ACTELION PHARMACEUTICALS LTD (CH) 2011-03-23 EP disclosed
US-20110065683-A1 TRISUBSTITUTED PYRAZOLES AS ACETYLCHOLINE RECEPTOR MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-03-17 US disclosed
US-20110046170-A1 NOVEL PYRIMIDINE-PYRIDINE DERIVATIVES ACTELION PHARMACEUTICALS LTD. (CH) 2011-02-24 US disclosed
US-20110046170-A1 NOVEL PYRIMIDINE-PYRIDINE DERIVATIVES ACTELION PHARMACEUTICALS LTD. (CH) 2011-02-24 US disclosed
WO-2009109907-A1 NOVEL PYRIMIDINE-PYRIDINE DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2009-09-11 WO disclosed
WO-2009024905-A1 PYRIDINE DERIVATIVES AS S1P1/EDG1 RECEPTOR MODULATORS ACTELION PHARMACEUTICALS LTD (CH) 2009-02-26 WO disclosed
CN-1090189-C pyrazolopyrimidines JANSSEN PHARMACEUTICA NV (BE) 2002-09-04 CN disclosed
CN-1205009-A Pyrazolopyrimidines type compound JANSSEN PHARMACEUTICA NV (BE) 1999-01-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110065683-A1 TRISUBSTITUTED PYRAZOLES AS ACETYLCHOLINE RECEPTOR MODULATORS CHRNA1, CHRM3, CHRNA5 MEN1 4651/4885KMT2A 2308/4885TSHR 91/4885
US-20110046170-A1 NOVEL PYRIMIDINE-PYRIDINE DERIVATIVES TYMP, DPYD, ENTPD5 MEN1 4570/4885KMT2A 3361/4885TSHR 2962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.