SCHEMBL989524

SCHEMBL989524

CNc1ccccc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29075918 0.97 ALDH1A1 (0.46)
SCHEMBL12525076 0.80 ALDH1A1 (0.44)
SCHEMBL29661757 0.79 L3MBTL1 (0.39)
SCHEMBL653948 0.78 POLB (0.60)
SCHEMBL29449705 0.78 POLB (0.60)
SCHEMBL14857685 0.77 ALDH1A1 (0.39)
SCHEMBL14861504 0.77 ALDH1A1 (0.39)
SCHEMBL27647088 0.77 MAPT (0.38)
SCHEMBL9226603 0.77 TAAR1 (0.52)
SCHEMBL20605197 0.77 L3MBTL1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677561-B 1,2,3, 4-tetrahydro-9-methyl-4H-carbazolone and synthesis method thereof 常州兰陵制药有限公司 2024-04-05 CN claimed
CN-115677561-A 1,2,3, 4-tetrahydro-9-methyl-4H-carbazolone and synthesis method thereof 常州兰陵制药有限公司 2023-02-03 CN claimed
CN-109851507-B Application of scandium-containing rare earth catalyst in catalysis of para-alkylation reaction of aromatic amine 苏州大学 2022-02-01 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
CN-108690032-A A kind of fluorescent dye and its synthetic method of azophenlyene fused structure 湖南大学 2018-10-23 CN claimed
CN-105693607-B A kind of synthetic method of 4- hydroxyls -8- bromo-isoquinolines 苏州康润医药有限公司 2018-09-11 CN claimed
CN-105693607-A Synthesis method of 4-hydroxy-8-bromoisoquinoline 苏州康润医药有限公司 2016-06-22 CN claimed
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-11-27 US disclosed
US-20250186408-A1 TREATMENT OF PHARMACORESISTANT EPILEPSY KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-06-12 US disclosed
US-20240400568-A1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES, INC. 2024-12-05 US disclosed
EP-4445902-A2 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS Carna Biosciences, Inc. (JP) 2024-10-16 EP disclosed
EP-4081305-B1 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS CARNA BIOSCIENCES INC (JP) 2024-09-18 EP disclosed
US-12054490-B2 Diacylglycerol kinase modulating compounds GILEAD SCIENCES, INC. (US) 2024-08-06 US disclosed
EP-0985664-A2 Method of producing pyrrolidine derivatives TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
EP-0970964-A2 Method for producing titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-01-12 EP disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed
EP-0934940-A1 CYTOKINE PRODUCTION INHIBITORS, TRIAZEPINE COMPOUNDS, AND INTERMEDIATES THEREOF Japan Tobacco Inc. (JP) 1999-08-11 EP disclosed
CN-1198746-A Tricyclic benzazepine * vasopressin antagonists AMERICAN CYANAMID CO (US) 1998-11-11 CN disclosed
US-5807850-A Therapeutic agent for osteoporosis and triazepine compound JAPAN TOBACCO, INC. (JP) 1998-09-15 US disclosed
EP-0792880-A1 OSTEOPOROSIS REMEDY AND TRIAZEPINE COMPOUND Japan Tobacco Inc. (JP) 1997-09-03 EP disclosed