Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28439911 | 0.86 | ALOX15 (0.31) | ALOX15 | |
| SCHEMBL14635030 | 0.73 | ALOX15 (0.32) | ALOX15TSHR | |
| SCHEMBL14635386 | 0.66 | — | — | |
| SCHEMBL9896407 | 0.58 | GBA1 (0.30) | — | |
| SCHEMBL21280997 | 0.57 | — | — | |
| SCHEMBL13342084 | 0.56 | — | — | |
| SCHEMBL15141912 | 0.54 | — | — | |
| Methyl Alcohol SCHEMBL1990695 | 0.53 | — | — | |
| Isobutanol SCHEMBL11800894 | 0.50 | TSHR (1.00) | TSHR | |
| Isobutanol SCHEMBL175952 | 0.50 | TSHR (1.00) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394997-B2 | Process for the isomerization of 2,2,4,4-tetraalkylcyclobutane-1,3-diols | EASTMAN CHEMICAL COMPANY (US) | 2013-03-12 | — | — | US | disclosed |
| WO-2012078439-A1 | PROCESS FOR THE ISOMERIZATION OF 2,2,4,4-TETRAALKYLCYCLOBUTANE-1,3-DIOLS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20120149948-A1 | PROCESS FOR THE ISOMERIZATION OF 2,2,4,4-TETRAALKYLCYCLOBUTANE-1,3-DIOLS | EASTMAN CHEMICAL COMPANY (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149948-A1 | PROCESS FOR THE ISOMERIZATION OF 2,2,4,4-TETRAALKYLCYCLOBUTANE-1,3-DIOLS | TRA2B, TFDP2, ADH1C | ALOX15 2413/4885TSHR 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.