Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.67 |
| ▸ | TBXAS1 | P24557 | 17/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12304848 | 0.84 | TBXAS1 (0.52) | EGLN3TBXAS1MEN1LMNAKMT2A | |
| SCHEMBL15223347 | 0.82 | EGLN3 (0.59) | EGLN3TBXAS1MEN1LMNAKMT2A | |
| SCHEMBL10072238 | 0.82 | TBXAS1 (0.59) | EGLN3TBXAS1MEN1LMNAKMT2A | |
| SCHEMBL47383 | 0.82 | EGLN3 (0.59) | EGLN3TBXAS1MEN1LMNAKMT2A | |
| SCHEMBL5859786 | 0.82 | TBXAS1 (0.55) | EGLN3TBXAS1LMNAALDH1A1 | |
| SCHEMBL10654651 | 0.82 | TDP1 (0.60) | TBXAS1KMT2AALDH1A1 | |
| SCHEMBL10653577 | 0.81 | TBXAS1 (0.58) | TBXAS1LMNA | |
| SCHEMBL2001103 | 0.81 | EGLN3 (1.00) | EGLN3TBXAS1ALDH1A1 | |
| SCHEMBL45921 | 0.81 | EGLN3 (0.57) | EGLN3TBXAS1 | |
| SCHEMBL47755 | 0.81 | EGLN3 (0.57) | EGLN3TBXAS1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12198346-B2 | Combining pH and metabolic activity imaging for response assessment in immune therapy | KONINKLIJKE PHILIPS N.V. (NL) | 2025-01-14 | — | — | US | disclosed |
| US-20200372653-A1 | COMBINING PH AND METABOLIC ACTIVITY IMAGING FOR RESPONSE ASSESSMENT IN IMMUNE THERAPY | KONINKLIJKE PHILIPS N.V. (NL) | 2020-11-26 | — | — | US | disclosed |
| EP-3509069-A1 | COMBINING PH AND METABOLIC ACTIVITY IMAGING FOR RESPONSE ASSESSMENT IN IMMUNE THERAPY | Koninklijke Philips N.V. (NL) | 2019-07-10 | — | — | EP | disclosed |
| US-20120148773-A1 | Thermoset Ionomer Derivatives of Halogenated Polymers | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-14 | — | — | US | disclosed |
| WO-2012075573-A1 | THERMOSET LONOMER DERIVATIVES OF HALOGENATED POLYMERS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2012-06-14 | — | — | WO | disclosed |