Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9899174 | 1.00 | CA2 (0.46) | CA2CA1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL9899580 | 0.88 | ALDH1A1 (0.46) | CA2CA1ALDH1A1L3MBTL1CA9 | |
| SCHEMBL9898715 | 0.88 | ALDH1A1 (0.46) | CA2CA1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9898714 | 0.88 | ALDH1A1 (0.46) | CA2CA1ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL9899578 | 0.88 | ALDH1A1 (0.46) | CA2CA1ALDH1A1L3MBTL1CA9 | |
| SCHEMBL9899083 | 0.85 | ALDH1A1 (0.50) | CA2CA1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL9899085 | 0.85 | ALDH1A1 (0.50) | CA2CA1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2042653 | 0.85 | NPC1 (0.47) | CA2CA1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL2042655 | 0.85 | NPC1 (0.47) | CA2CA1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL9899495 | 0.84 | KDM4E (0.45) | ALDH1A1L3MBTL1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | claimed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | claimed |
| EP-2649102-B1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORP (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8748531-B2 | Polymers functionalized with oxime compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2014-06-10 | — | — | US | disclosed |
| US-20120149833-A1 | POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP | BRIDGESTONE CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |