SCHEMBL990

SCHEMBL990

CCOc1ccccc1C(=O)Cl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.62
L3MBTL1 Q9Y468 4/20 0.55
GLA P06280 1/20 0.55
MAPT P10636 5/20 0.54
MAPK1 P28482 3/20 0.54
GAA P10253 2/20 0.54
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
NPSR1 Q6W5P4 1/20 0.53
ALDH1A1 P00352 2/20 0.51
HPGD P15428 2/20 0.51
HSD17B10 Q99714 2/20 0.51
LMNA P02545 1/20 0.51
KDM4E B2RXH2 2/20 0.51
HTT P42858 1/20 0.51
TSHR P16473 3/20 0.50
ALOX15 P16050 2/20 0.50
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
RAB9A P51151 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14244495 0.86 HCRTR1 (0.47) HCRTR1L3MBTL1MAPTMAPK1GAA
SCHEMBL1985 0.85 LMNA (0.55) HCRTR1L3MBTL1MAPTMEN1KMT2A
SCHEMBL20150685 0.84 ABCB1 (0.64) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL206583 0.84 HCRTR1 (0.66) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL11763044 0.84 HCRTR1 (0.66) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL6969031 0.84 HCRTR1 (0.66) HCRTR1L3MBTL1GLAMAPTMAPK1
Hydrochloric Acid SCHEMBL27771056 0.84 LMNA (0.54) HCRTR1L3MBTL1MAPTMEN1KMT2A
SCHEMBL5827955 0.84 LMNA (0.62) L3MBTL1MAPTMAPK1MEN1KMT2A
SCHEMBL27574878 0.84 HCRTR1 (0.49) HCRTR1L3MBTL1GLAMAPTMAPK1
SCHEMBL30292656 0.82 LMNA (0.71) HCRTR1L3MBTL1GLAMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 485 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756625-B Preparation method of o-ethoxybenzoyl chloride 达高工业技术研究院(广州)有限公司 2024-06-18 CN claimed
CN-117756625-A Preparation method of o-ethoxybenzoyl chloride 达高工业技术研究院(广州)有限公司 2024-03-26 CN claimed
CN-112239653-B Fluid loss additive for drilling fluid based on nanofiber-hydrophobic starch compound and preparation method thereof 中石化石油工程技术服务有限公司 2022-07-08 CN claimed
CN-112239653-A Fluid loss additive for drilling fluid based on nanofiber-hydrophobic starch compound and preparation method thereof 中石化石油工程技术服务有限公司 2021-01-19 CN claimed
CN-111548263-A Process method for preparing o-ethoxy benzoyl chloride 江苏巨莱生物医药有限公司 2020-08-18 CN claimed
CN-111116591-A Method for preparing sildenafil citrate 天津科伦药物研究有限公司 2020-05-08 CN claimed
US-9512242-B2 Polymerizable oligomer and photoresist composition comprising the same BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-12-06 US claimed
CN-104194398-B Fluorescent dichroic dye containing 4- (p-hydroxypiperidinyl) -1, 8-naphthaline dinitrile, preparation method and application thereof DALIAN UNIVERSITY OF TECHNOLOGY (CN) 2016-06-01 CN claimed
US-20160137758-A1 POLYMERIZABLE OLIGOMER AND PHOTORESIST COMPOSITION COMPRISING THE SAME BOE TECHNOLOGY GROUP CO., LTD. (CN) 2016-05-19 US claimed
CN-104194398-A Fluorescent dichroic dye containing 4- (p-hydroxypiperidinyl) -1, 8-naphthaline dinitrile, preparation method and application thereof UNIV DALIAN TECH 2014-12-10 CN claimed
WO-2006127368-A2 METHODS FOR SYNTHESIZING IMIDAZOTRIAZINONES LEXICON GENETICS INCORPORATED (US) 2006-11-30 WO claimed
US-20060264624-A1 Methods for synthesizing imidazotriazinones LEXICON GENETICS INCORPORATED 2006-11-23 US claimed
US-4362510-A ESTER OF VANILLIC ACID, METAL OXIDE OR HYDROXIDE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1982-12-07 US claimed
CN-117777023-B Preparation method and application of aminopyrazole compound 山东特珐曼药业有限公司 2026-05-19 CN disclosed
CN-121955254-A Method for detecting 2-ethoxybenzoyl chloride and related substances thereof 广药白云山化学制药(珠海)有限公司 2026-05-01 CN disclosed
CN-121955254-A Method for detecting 2-ethoxybenzoyl chloride and related substances thereof 广药白云山化学制药(珠海)有限公司 2026-05-01 CN disclosed
CN-1057464-A Pyrazolopyrimidinoneantianginal antianginal agents PFIZER (US) 1992-01-01 CN disclosed
US-4058523-A ANTIULCER, VASODILATION, HYPOTENSIVE, ANALGESIC CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1977-11-15 US disclosed
US-3953496-A ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) 1976-04-27 US disclosed
US-3939162-A Anthrapyrimidine dyes BASF AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264624-A1 Methods for synthesizing imidazotriazinones PDE3A, PDE2A, PDE3B HCRTR1 4355/4885L3MBTL1 4829/4885GLA 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.