SCHEMBL9900237

SCHEMBL9900237

C#Cc1cc2c([Si](CC)(CC)CC)c3c(ccc4ccccc43)c([Si](CC)(CC)CC)c2c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
RAB9A P51151 1/20 0.33
CASP7 P55210 1/20 0.33
ATM Q13315 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CYP1A2 P05177 2/20 0.31
CYP1A1 P04798 1/20 0.31
CYP1B1 Q16678 1/20 0.31
ERBB2 P04626 1/20 0.30
FYN P06241 1/20 0.30
MAOA P21397 1/20 0.30
ACHE P22303 1/20 0.30
AHR P35869 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9899758 0.85 HSD17B10 (0.36) HPGDL3MBTL1CYP3A4TSHRMAPK1
SCHEMBL9900279 0.84 L3MBTL1 (0.35) HPGDL3MBTL1CYP3A4TSHRMAPK1
SCHEMBL15797402 0.70 HSD17B10 (0.45) HPGDL3MBTL1CYP3A4TSHRMAPK1
SCHEMBL2541430 0.68
SCHEMBL3721466 0.67
SCHEMBL2541426 0.66 CYP1A1 (0.40) CYP1A2CYP1A1CYP1B1
SCHEMBL6129153 0.63 HSD17B10 (0.48) HPGDL3MBTL1CYP3A4TSHRMAPK1
SCHEMBL1933777 0.63 HPRT1 (0.58) HPGDCYP3A4TSHRMAPK1HIF1A
SCHEMBL12405250 0.62 HPRT1 (0.52) HPGDL3MBTL1CYP3A4TSHRMAPK1
SCHEMBL5012544 0.62 CYP2A6 (0.39) HPGDL3MBTL1CYP3A4TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2649082-B1 NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2015-01-14 EP disclosed
EP-2649082-A1 NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS Merck Patent GmbH (DE) 2013-10-16 EP disclosed
US-20130248771-A1 NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2013-09-26 US disclosed
WO-2012076092-A1 NON-LINEAR ACENE DERIVATIVES AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2012-06-14 WO disclosed