SCHEMBL5012544

SCHEMBL5012544

C#Cc1ccc2ccccc2c1[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 5/20 0.39
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
HSD17B10 Q99714 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
HPRT1 P00492 1/20 0.37
CYP1A2 P05177 3/20 0.35
CYP1B1 Q16678 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP1A1 P04798 1/20 0.33
CYP3A4 P08684 2/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
CASP1 P29466 1/20 0.32
RAB9A P51151 1/20 0.32
CASP7 P55210 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3465692 0.76 NQO1 (0.33) ALDH1A1MAPTHPGDRAB9A
SCHEMBL5014199 0.75 CYP1A2 (0.39) CYP2A6ALDH1A1TSHRHSD17B10CYP1A2
SCHEMBL9899758 0.75 HSD17B10 (0.36) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL9900279 0.74 L3MBTL1 (0.35) ALDH1A1TSHRHSD17B10TDP1HPRT1
SCHEMBL27632078 0.72 CYP2A6 (0.46) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL31676618 0.72 CYP2A6 (0.46) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL5431973 0.72 CYP2A6 (0.46) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL689190 0.71 ALDH1A1 (0.44) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL7940388 0.71 PTPN22 (0.54) CYP2A6ALDH1A1TSHRHSD17B10TDP1
SCHEMBL16841267 0.70 ALDH1A1 (0.45) CYP2A6ALDH1A1TSHRHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1389626-B1 Aromatic copolymers of pyrroles and an electroluminescent element using the same KOREA INST SCI & TECH (KR) 2008-12-31 EP disclosed
EP-1389626-A1 Aromatic copolymers of pyrroles and an electroluminescent element using the same Korea Institute of Science and Technology (KR) 2004-02-18 EP disclosed