SCHEMBL9900249

SCHEMBL9900249

CC(=O)O/N=C(\C)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 9/20 0.52
CES1 P23141 8/20 0.52
L3MBTL1 Q9Y468 4/20 0.47
KMT2A Q03164 2/20 0.47
ELANE P08246 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
MAPT P10636 4/20 0.41
PKM P14618 1/20 0.41
CDK5 Q00535 1/20 0.41
CDK5R1 Q15078 1/20 0.41
TSHR P16473 2/20 0.41
LMNA P02545 3/20 0.41
ALDH1A1 P00352 2/20 0.41
RAB9A P51151 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
GLA P06280 1/20 0.41
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194894 1.00 CES2 (0.52) CES2CES1L3MBTL1KMT2AELANE
SCHEMBL194893 1.00 CES2 (0.52) CES2CES1L3MBTL1KMT2AELANE
SCHEMBL18978830 0.93 KMT2A (0.57) CES2CES1L3MBTL1KMT2ASMN1; SMN2
SCHEMBL16690274 0.90 SMN1; SMN2 (0.57) CES2CES1L3MBTL1KMT2ASMN1; SMN2
SCHEMBL195166 0.87 KMT2A (0.62) CES2CES1L3MBTL1KMT2ASMN1; SMN2
SCHEMBL20278523 0.87 KMT2A (0.62) CES2CES1L3MBTL1KMT2ASMN1; SMN2
SCHEMBL195165 0.87 KMT2A (0.62) CES2CES1L3MBTL1KMT2ASMN1; SMN2
SCHEMBL16019156 0.85 HPGD (0.56) CES2CES1L3MBTL1KMT2AELANE
SCHEMBL19795435 0.85 HPGD (0.56) CES2CES1L3MBTL1KMT2AELANE
SCHEMBL12288110 0.85 CES2 (0.48) CES2CES1L3MBTL1KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US claimed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US claimed
CN-117486836-A Preparation method of 2-aryl-3-carbonyl substituted tetrahydrofuran and tetrahydropyran compound 遵义医科大学 2024-02-02 CN disclosed
EP-2649102-B1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORP (JP) 2014-11-26 EP disclosed
US-8748531-B2 Polymers functionalized with oxime compounds containing an acyl group BRIDGESTONE CORPORATION (JP) 2014-06-10 US disclosed
US-20120149833-A1 POLYMERS FUNCTIONALIZED WITH OXIME COMPOUNDS CONTAINING AN ACYL GROUP BRIDGESTONE CORPORATION (JP) 2012-06-14 US disclosed
EP-1095313-B1 PHOTOPOLYMERIZABLE THERMOSETTING RESIN COMPOSITIONS CIBA SC HOLDING AG (CH) 2008-03-05 EP disclosed