Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.52 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | C5 | P01031 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741874 | 0.87 | MDM2 (0.44) | PTGS2PTGS1APPPPARGPPARA | |
| SCHEMBL29858584 | 0.81 | LMNA (0.55) | PTGS2PTGS1MEN1ABCC4C5 | |
| SCHEMBL838637 | 0.81 | LMNA (0.55) | PTGS2PTGS1MEN1ABCC4C5 | |
| SCHEMBL15641246 | 0.81 | LMNA (0.55) | PTGS2PTGS1MEN1ABCC4C5 | |
| SCHEMBL19182930 | 0.81 | PTGS1 (0.54) | PTGS2PTGS1PSEN1PSEN2APH1B | |
| SCHEMBL31117279 | 0.81 | PTGS1 (0.54) | PTGS2PTGS1PSEN1PSEN2APH1B | |
| SCHEMBL19182931 | 0.81 | PTGS1 (0.54) | PTGS2PTGS1PSEN1PSEN2APH1B | |
| SCHEMBL7894763 | 0.81 | PPARG (0.47) | PPARGPPARAMDM2KMT2A | |
| SCHEMBL16219361 | 0.80 | PTGS1 (0.52) | PTGS2PTGS1APPPSEN1PSEN2 | |
| SCHEMBL16207512 | 0.80 | PTGS2 (0.52) | PTGS2PTGS1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106748725-B | preparation method of 4-chloro-2-fluoro-phenylpropionic acid | 贵州大学 | 2020-01-31 | — | — | CN | claimed |
| CN-106748725-B | preparation method of 4-chloro-2-fluoro-phenylpropionic acid | 贵州大学 | 2020-01-31 | — | — | CN | disclosed |
| CN-106748725-B | preparation method of 4-chloro-2-fluoro-phenylpropionic acid | 贵州大学 | 2020-01-31 | — | — | CN | disclosed |
| CN-106748725-B | preparation method of 4-chloro-2-fluoro-phenylpropionic acid | 贵州大学 | 2020-01-31 | — | — | CN | disclosed |
| EP-2649045-B1 | SUBSTITUTED 1-BENZYLCYCLOALKYLCARBOXLIC ACIDS AND USE THEREOF | BAYER IP GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| EP-2649045-A2 | SUBSTITUTED 1-BENZYLCYCLOALKYLCARBOXLIC ACIDS AND USE THEREOF | Bayer Intellectual Property GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076466-A2 | SUBSTITUTED 1-BENZYLCYCLOALKYLCARBOXLIC ACIDS AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-06-14 | — | — | WO | disclosed |