Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 13/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL990881 | 0.86 | LMNA (0.50) | LMNAGRM5NPC1RAB9AL3MBTL1 | |
| SCHEMBL990361 | 0.86 | LMNA (0.50) | LMNAGRM5NPC1RAB9AL3MBTL1 | |
| SCHEMBL990865 | 0.86 | NPC1 (0.46) | LMNAGRM5NPC1RAB9AL3MBTL1 | |
| SCHEMBL3376114 | 0.85 | GRM5 (0.44) | GRM5 | |
| SCHEMBL990882 | 0.83 | GRM5 (0.45) | GRM5NPC1RAB9AL3MBTL1 | |
| SCHEMBL990968 | 0.83 | GRM5 (0.45) | GRM5RAB9AL3MBTL1 | |
| SCHEMBL992077 | 0.83 | GRM5 (0.44) | GRM5NPC1RAB9AL3MBTL1 | |
| SCHEMBL990821 | 0.83 | GRM5 (0.44) | GRM5 | |
| SCHEMBL990212 | 0.83 | GRM5 (0.44) | GRM5NPC1RAB9AL3MBTL1 | |
| SCHEMBL990179 | 0.82 | GRM5 (0.46) | GRM5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272509-A1 | New Uses of metabotropic glutamate receptors | Novartis AG (CH) | 2011-01-12 | — | — | EP | disclosed |