⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901211 | 0.85 | — | — | |
| SCHEMBL29437993 | 0.78 | HTR1A (0.31) | — | |
| SCHEMBL9901496 | 0.78 | HTR1A (0.31) | — | |
| SCHEMBL9901104 | 0.77 | HTR1A (0.34) | — | |
| SCHEMBL15303180 | 0.73 | — | — | |
| SCHEMBL16193623 | 0.72 | — | — | |
| SCHEMBL17188995 | 0.70 | HTR1A (0.31) | — | |
| SCHEMBL23027450 | 0.67 | HTR1A (0.36) | — | |
| SCHEMBL15011718 | 0.67 | HTR1A (0.36) | — | |
| SCHEMBL20994824 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649066-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | Autifony Therapeutics Limited (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076877-A1 | HYDANTOIN DERIVATIVES USEFUL AS KV3 INHIBITORS | AUTIFONY THERAPEUTICS LIMITED (GB) | 2012-06-14 | — | — | WO | disclosed |