Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15011718 | 0.79 | HTR1A (0.36) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL15011716 | 0.79 | HTR1A (0.36) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL31566437 | 0.79 | HTR1A (0.31) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL23027449 | 0.79 | TP53 (0.32) | — | |
| SCHEMBL22650791 | 0.70 | PTGS1 (0.36) | HTR1A | |
| SCHEMBL29437993 | 0.69 | HTR1A (0.31) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL9901496 | 0.69 | HTR1A (0.31) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL17188995 | 0.69 | HTR1A (0.31) | HTR1AHTR7HTR2BTMEM97SIGMAR1 | |
| SCHEMBL10440200 | 0.69 | NR3C1 (0.35) | — | |
| SCHEMBL1764329 | 0.68 | HTR1A (0.33) | HTR1AHTR7HTR2BTMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021032074-A1 | BENZAMIDE FUSED AROMATIC RING DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF IN MEDICINE | 江苏恒瑞医药股份有限公司 | 2021-02-25 | — | — | WO | disclosed |