Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901547 | 0.77 | CYP1A2 (0.30) | — | |
| SCHEMBL1166849 | 0.71 | CYP1A2 (0.38) | — | |
| SCHEMBL856703 | 0.70 | CYP1A2 (0.30) | — | |
| SCHEMBL3433894 | 0.70 | USP7 (0.34) | SCN5AUSP7 | |
| SCHEMBL10203078 | 0.69 | SCN5A (0.34) | SCN5AUSP7 | |
| SCHEMBL9900516 | 0.69 | CYP1A2 (0.31) | — | |
| SCHEMBL20305583 | 0.69 | CA1 (0.36) | — | |
| SCHEMBL9722863 | 0.68 | TACR1 (0.33) | SCN5A | |
| SCHEMBL1707146 | 0.67 | CYP1A2 (0.43) | — | |
| SCHEMBL31740772 | 0.66 | CHRNA7 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648724-A1 | HYDROXYLATED AMINOTRIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077051-A1 | HYDROXYLATED AMINOTRIAZOLE DERIVATIVES AS ALX RECEPTOR AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2012-06-14 | — | — | WO | disclosed |