Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901030 | 0.91 | MAPKAPK2 (0.38) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9112136 | 0.87 | MAPKAPK2 (0.43) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905107 | 0.84 | MAPKAPK2 (0.38) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9111137 | 0.83 | MAPKAPK2 (0.44) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905675 | 0.82 | MAPK14 (0.44) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905046 | 0.82 | MAPKAPK2 (0.36) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9111121 | 0.81 | MAPKAPK5 (0.52) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9109919 | 0.80 | MAPK14 (0.42) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9112127 | 0.79 | MAPKAPK2 (0.40) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9109194 | 0.79 | MAPKAPK5 (0.57) | MAPKAPK2MAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648516-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Confluence Life Sciences, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078684-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | CONFLUENCE LIFE SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | disclosed |