Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905107 | 0.93 | MAPKAPK2 (0.38) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901655 | 0.91 | MAPKAPK2 (0.37) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9111805 | 0.86 | MAPKAPK2 (0.45) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905046 | 0.86 | MAPKAPK2 (0.36) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901203 | 0.85 | GABRG2 (0.30) | — | |
| SCHEMBL9905675 | 0.84 | MAPK14 (0.44) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9109954 | 0.82 | MAPKAPK2 (0.46) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905063 | 0.80 | GRM5 (0.31) | — | |
| SCHEMBL9110095 | 0.80 | MAPKAPK5 (0.54) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901137 | 0.79 | MAPKAPK2 (0.36) | MAPKAPK2MAPKAPK5ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648516-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Confluence Life Sciences, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012078684-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | CONFLUENCE LIFE SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | disclosed |