Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901030 | 0.86 | MAPKAPK2 (0.38) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905675 | 0.85 | MAPK14 (0.44) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9902078 | 0.83 | MAPKAPK2 (0.38) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901655 | 0.82 | MAPKAPK2 (0.37) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901821 | 0.82 | THRA (0.34) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901327 | 0.81 | MAOB (0.37) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905107 | 0.78 | MAPKAPK2 (0.38) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9109152 | 0.77 | MAPK14 (0.47) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9905630 | 0.76 | MAPKAPK2 (0.48) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL9901647 | 0.76 | MAOB (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2648516-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | Confluence Life Sciences, Inc. (US) | 2013-10-16 | — | — | EP | claimed |
| WO-2012078684-A1 | SUBSTITUTED PYRIDINONE-PYRIDINYL COMPOUNDS | CONFLUENCE LIFE SCIENCES, INC. (US) | 2012-06-14 | — | — | WO | claimed |