Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 19/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 12/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9902313 | 0.93 | SCN10A (0.39) | SCN10AJAK2JAK1TYK2SCN8A | |
| SCHEMBL9901557 | 0.76 | CTSL (0.46) | — | |
| SCHEMBL9902320 | 0.76 | ALDH1A1 (0.39) | JAK2JAK1TYK2 | |
| SCHEMBL9902968 | 0.74 | EPHX1 (0.41) | — | |
| SCHEMBL9902487 | 0.70 | ALDH1A1 (0.47) | — | |
| SCHEMBL9901615 | 0.68 | ALDH1A1 (0.40) | JAK2JAK1TYK2 | |
| SCHEMBL9901315 | 0.67 | ALDH1A1 (0.50) | — | |
| SCHEMBL9902117 | 0.66 | ALDH1A1 (0.46) | — | |
| SCHEMBL13373625 | 0.66 | JAK2 (0.54) | JAK2JAK1TYK2 | |
| SCHEMBL9903173 | 0.65 | EPHX1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649048-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | Radikal Therapeutics Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012077108-A1 | MULTIFUNCTIONAL NITROXIDE DERIVATIVES AND USES THEREOF | RADIKAL THERAPEUTICS INC. (US) | 2012-06-14 | — | — | WO | disclosed |