Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.58 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.58 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PLK1 | P53350 | 4/20 | 0.39 |
| ▸ | UNG | P13051 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900998 | 1.00 | LPL (0.58) | LPLLIPGTHRATHRBPLK1 | |
| SCHEMBL20829056 | 0.78 | LPL (0.43) | LPLLIPGMAPTSLC6A2KDM4E | |
| SCHEMBL9901870 | 0.77 | LPL (0.44) | LPLLIPGLMNACYP3A4CHRM2 | |
| SCHEMBL20829077 | 0.76 | LIPG (0.54) | LPLLIPGMAPTKDM4E | |
| SCHEMBL19001570 | 0.74 | LPL (1.00) | LPLLIPGHTR2AESR1ADRA2A | |
| SCHEMBL18727878 | 0.74 | LPL (1.00) | LPLLIPGHTR2AESR1ADRA2A | |
| SCHEMBL14227371 | 0.74 | LPL (1.00) | LPLLIPGHTR2AESR1ADRA2A | |
| SCHEMBL1353091 | 0.74 | LPL (1.00) | LPLLIPGHTR2AESR1ADRA2A | |
| SCHEMBL1513184 | 0.74 | LPL (1.00) | LPLLIPGHTR2AESR1ADRA2A | |
| SCHEMBL18462914 | 0.74 | LPL (0.67) | LPLLIPGHTR2AMAPTESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649073-A2 | PROCESS FOR THE PREPARATION OF SEMICONDUCTOR MATERIALS, COMPOUNDS AND THEIR USE | The University Of Manchester (GB) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076886-A2 | NOVEL PROCESS AND COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012076886-A2 | NOVEL PROCESS AND COMPOUNDS | THE UNIVERSITY OF MANCHESTER (GB) | 2012-06-14 | — | — | WO | disclosed |