Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824404 | 0.81 | ALDH1A1 (0.35) | ALDH1A1PKMSLC1A2KMT2ACYP2C9 | |
| SCHEMBL23716973 | 0.75 | ALDH1A1 (0.46) | ALDH1A1PKMSLC1A2KMT2AMEN1 | |
| SCHEMBL31259418 | 0.75 | ALDH1A1 (0.46) | ALDH1A1PKMSLC1A2KMT2AMEN1 | |
| SCHEMBL432176 | 0.73 | ALDH1A1 (0.44) | ALDH1A1PKMSLC1A2KMT2AMEN1 | |
| SCHEMBL202493 | 0.71 | ALDH1A1 (0.43) | ALDH1A1PKMSLC1A2KMT2AMEN1 | |
| SCHEMBL1442379 | 0.71 | ALDH1A1 (0.43) | ALDH1A1PKMSLC1A2KMT2AMEN1 | |
| SCHEMBL1564214 | 0.71 | KMT2A (0.53) | ALDH1A1PKMSLC1A2KMT2AHSD17B10 | |
| SCHEMBL57078 | 0.71 | KMT2A (0.53) | ALDH1A1PKMSLC1A2KMT2AHSD17B10 | |
| SCHEMBL526394 | 0.71 | ALDH1A1 (0.43) | ALDH1A1PKMSLC1A2KMT2AMEN1 | |
| SCHEMBL6032556 | 0.71 | DNMT1 (0.34) | ALDH1A1KMT2AHPGDHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021004975-A1 | MODIFIED IgA ANTIBODY PROTEINS | UNIVERSITETET I OSLO (NO) | 2021-01-14 | — | — | WO | disclosed |
| EP-2649097-A1 | ANTI CCR4 ANTIBODIES AND USES THEREOF | Affitech Research AS (NO) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076883-A1 | ANTI CCR4 ANTIBODIES AND USES THEREOF | AFFITECH RESEARCH AS (NO) | 2012-06-14 | — | — | WO | disclosed |