SCHEMBL1824404

SCHEMBL1824404

O=C(S)C(S)N1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
PKM P14618 1/20 0.35
CYP2D6 P10635 1/20 0.32
CYP2C9 P11712 1/20 0.32
SLC1A2 P43004 1/20 0.31
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9901995 0.81 ALDH1A1 (0.43) ALDH1A1PKMCYP2C9SLC1A2KMT2A
SCHEMBL28393846 0.73 ALDH1A1 (0.37) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL7164891 0.71 CYP2D6 (0.33) ALDH1A1PKMCYP2D6CYP2C9SLC1A2
SCHEMBL2913712 0.67 ALDH1A1 (0.40) ALDH1A1PKMCYP2D6CYP2C9SLC1A2
SCHEMBL8749736 0.67 CHRM2 (0.37) ALDH1A1PKMCYP2D6CYP2C9SLC1A2
SCHEMBL3487387 0.67 KMT2A (0.44) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL5154460 0.66 ALDH1A1 (0.36) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL8212689 0.66 ALDH1A1 (0.36) ALDH1A1PKMSLC1A2KMT2AATM
SCHEMBL23716973 0.65 ALDH1A1 (0.46) ALDH1A1PKMCYP2D6CYP2C9SLC1A2
SCHEMBL31259418 0.65 ALDH1A1 (0.46) ALDH1A1PKMCYP2D6CYP2C9SLC1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1867300-A2 Intracorporeal occlusive device Sethel Interventional, Inc. (US) 2007-12-19 EP claimed
EP-1200012-A2 INTRACORPOREAL OCCLUSIVE DEVICE Sethel Interventional, Inc. (US) 2002-05-02 EP claimed
WO-2000072781-A2 INTRACORPOREAL OCCLUSIVE DEVICE SETHEL INTERVENTIONAL, INC. (US) 2000-12-07 WO claimed
US-20240042194-A1 Methods of Implanting a Device into a Brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-02-08 US disclosed
US-11648394-B2 Methods of implanting a device into a brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-05-16 US disclosed
US-20210361935-A1 Methods of Implanting a Device into a Brain THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-11-25 US disclosed
US-9788840-B2 Intracorporeal occlusive device and method Marks, Michael P. (US) 2017-10-17 US disclosed
US-9526505-B2 Intracorporeal occlusive device and method MICROVENTION, INC. (US) 2016-12-27 US disclosed
EP-1992308-B1 Intracorporeal occlusive device MICROTRANSFORM INC (US) 2015-10-28 EP disclosed
US-20150173771-A1 Intracorporeal Occlusive Device And Method MARKS, MICHAEL P. 2015-06-25 US disclosed
US-8932317-B2 Intracorporeal occlusive device and method MICROVENTION, INC. (US) 2015-01-13 US disclosed
WO-2002043616-A2 STENT DEVICES WITH DETACHABLE DISTAL OR PROXIMAL WIRES SCIMED LIFE SYSTEMS, INC. (US) 2002-06-06 WO disclosed
EP-1200012-A2 INTRACORPOREAL OCCLUSIVE DEVICE Sethel Interventional, Inc. (US) 2002-05-02 EP disclosed
US-20020040235-A1 Endovascular apparatus HOLMAN THOMAS J (US) 2002-04-04 US disclosed
US-6319276-B1 Endovascular apparatus SCIMED LIFE SYSTEMS, INC. 2001-11-20 US disclosed
WO-2000072781-A2 INTRACORPOREAL OCCLUSIVE DEVICE SETHEL INTERVENTIONAL, INC. (US) 2000-12-07 WO disclosed
US-6059823-A Endovascular apparatus SCIMED LIFE SYSTEMS, INC. (US) 2000-05-09 US disclosed
EP-0959810-A1 ENDOVASCULAR APPARATUS SciMed Life Systems, Inc. (US) 1999-12-01 EP disclosed
US-5871537-A Endovascular apparatus SCIMED LIFE SYSTEMS, INC. (US) 1999-02-16 US disclosed
WO-1997029716-A1 ENDOVASCULAR APPARATUS SCIMED LIFE SYSTEMS, INC. (US) 1997-08-21 WO disclosed