Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 2/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17416639 | 0.85 | CYP1A2 (0.42) | ABCB1RAB9AALDH1A1HPGD | |
| SCHEMBL5058555 | 0.80 | ABCB1 (0.58) | ABCB1CYP3A4HPGD | |
| SCHEMBL668612 | 0.73 | ABCB1 (0.71) | ABCB1CYP3A4HPGD | |
| SCHEMBL4439209 | 0.70 | ABCB1 (0.63) | ABCB1CYP3A4HPGD | |
| SCHEMBL5064387 | 0.70 | HPGD (0.63) | ABCB1CYP3A4POLBHPGD | |
| SCHEMBL5056941 | 0.70 | HPGD (0.56) | ABCB1CYP3A4POLBHPGD | |
| SCHEMBL5209743 | 0.69 | ABCB1 (0.57) | ABCB1CYP3A4RAB9APOLBHPGD | |
| SCHEMBL10139352 | 0.68 | HPGD (0.54) | ABCB1CYP3A4HPGD | |
| SCHEMBL5058463 | 0.68 | ABCB1 (0.49) | ABCB1HPGD | |
| SCHEMBL5057388 | 0.68 | ABCB1 (0.56) | ABCB1CYP3A4ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-13 | — | — | EP | disclosed |