Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9901775 | 0.85 | NOTUM (0.58) | NOTUMCHRNB2CHRNA4RAB9ASMN1; SMN2 | |
| SCHEMBL9902277 | 0.82 | NOTUM (0.35) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19143311 | 0.78 | ADRB2 (0.37) | NOTUMRAB9ASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL4050311 | 0.75 | NOTUM (0.74) | NOTUMRAB9ASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL9903239 | 0.74 | NOTUM (0.34) | NOTUMRAB9ASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL19336747 | 0.74 | RAB9A (0.41) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL19143242 | 0.74 | MAPK1 (0.45) | NOTUMRAB9ASMN1; SMN2MAPK1KMT2A | |
| Lithium Ion SCHEMBL30047029 | 0.72 | NOTUM (0.70) | NOTUMRAB9ASMN1; SMN2MAPK1KMT2A | |
| SCHEMBL3955619 | 0.69 | NOTUM (0.51) | NOTUMCHRNB2CHRNA4RAB9ASMN1; SMN2 | |
| SCHEMBL4041589 | 0.69 | NOTUM (0.51) | NOTUMCHRNB2CHRNA4RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673285-A1 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |