Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Taurine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.70 |
| ▸ | BLM | P54132 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Taurine SCHEMBL1826395 | 0.92 | LMNA (0.82) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL7213501 | 0.92 | LMNA (0.82) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL27709203 | 0.90 | LMNA (0.78) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL8698527 | 0.87 | LMNA (0.82) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL28279946 | 0.87 | — | — | |
| Taurine SCHEMBL7107903 | 0.87 | — | — | |
| Taurine SCHEMBL28258700 | 0.87 | — | — | |
| Taurine SCHEMBL2422017 | 0.87 | — | — | |
| Taurine SCHEMBL8052521 | 0.87 | BLM (0.93) | LMNASLC6A6CYP2C19BLMAPP | |
| Taurine SCHEMBL30179154 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635905-A2 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | AbbVie Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012078270-A2 | EFFICIENT AND EFFECTIVE SUPPLEMENT SCREENING FOR THE DEVELOPMENT OF CHEMICALLY DEFINED MEDIA IN CELL CULTURE | ABBOTT LABORATORIES (ES) | 2012-06-14 | — | — | WO | disclosed |