SCHEMBL990235

SCHEMBL990235

Nc1ccc(C(Cl)c2ccc(N)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CYP3A4 P08684 8/20 0.42
TDP1 Q9NUW8 7/20 0.42
ALDH1A1 P00352 6/20 0.42
TP53 P04637 2/20 0.42
MAPK1 P28482 4/20 0.38
ALOX15 P16050 3/20 0.38
HSD17B10 Q99714 2/20 0.38
ACHE P22303 1/20 0.38
CA3 P07451 1/20 0.38
THRB P10828 1/20 0.38
CA6 P23280 1/20 0.38
CASP1 P29466 1/20 0.38
HIF1A Q16665 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TSHR P16473 5/20 0.36
RAB9A P51151 2/20 0.36
GFER P55789 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407921 0.81 TSHR (0.50) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL677868 0.77 MEN1 (0.44) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL21380591 0.77 CYP3A4 (0.36) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL22050356 0.73 MEN1 (0.57) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL1596487 0.73 MAPT (0.57) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL223522 0.73 MEN1 (0.57) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL5955 0.71 MAPT (0.53) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL12461779 0.71 MEN1 (0.53) MAPTMEN1KMT2ACYP3A4TDP1
SCHEMBL1573440 0.71 TSHR (0.60) MAPTCYP3A4TDP1TP53MAPK1
SCHEMBL9663050 0.71 MEN1 (0.53) MAPTMEN1KMT2ACYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190292362-A1 Catalytically Active Radical Scavengers Based on Benzylic and Allylic Functionalities HOLLAND NOVOCHEM TECHNICAL COATINGS B.V. (NL) 2019-09-26 US disclosed
CN-109790323-A Catalytically active radical scavengers based on benzyl and allyl functional groups 荷兰诺沃赫姆技术涂料私人有限公司 2019-05-21 CN disclosed
EP-3102561-A1 AMINE FOR LOW-EMISSION EPOXY RESIN PRODUCTS Sika Technology AG (CH) 2016-12-14 EP disclosed
EP-2943518-A2 HARDENERS FOR LOW-EMISSION EPOXY RESIN PRODUCTS Sika Technology AG (CH) 2015-11-18 EP disclosed
EP-2943519-A2 HARDENERS FOR LOW-EMISSION EPOXY RESIN PRODUCTS Sika Technology AG (CH) 2015-11-18 EP disclosed
WO-2015117846-A1 AMINE FOR LOW-EMISSION EPOXY RESIN PRODUCTS SIKA TECHNOLOGY AG (CH) 2015-08-13 WO disclosed
WO-2014108304-A2 HARDENERS FOR LOW-EMISSION EPOXY RESIN PRODUCTS SIKA TECHNOLOGY AG (CH) 2014-07-17 WO disclosed
WO-2014108305-A2 HARDENERS FOR LOW-EMISSION EPOXY RESIN PRODUCTS SIKA TECHNOLOGY AG (CH) 2014-07-17 WO disclosed
EP-2454304-A2 FORMAMIDE-CONTAINING REACTIVE SYSTEMS Bayer MaterialScience AG (DE) 2012-05-23 EP disclosed
WO-2011006607-A2 FORMAMIDE-CONTAINING REACTIVE SYSTEMS BAYER MATERIALSCIENCE AG (DE) 2011-01-20 WO disclosed
WO-2001005883-A1 COMPACT AND/OR CELLULAR POLYURETHANE ELASTOMERS WITH NANOSCALE FILLERS BAYER AKTIENGESELLSCHAFT (DE) 2001-01-25 WO disclosed
EP-0309866-A2 Process for the preparation of RTV polyurethane urea elastomers BAYER AG (DE) 1989-04-05 EP disclosed
EP-0309865-A2 Process for the preparation of thermally stable polyurethane-polyurea elastomers BAYER AG (DE) 1989-04-05 EP disclosed
US-4294934-A CASTING COMPOSITION BAYER AKTIENGESELLSCHAFT (DE) 1981-10-13 US disclosed