Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18091873 | 0.94 | NPC1 (0.39) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL2683648 | 0.93 | ABCB1 (0.36) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL29684859 | 0.93 | ABCB1 (0.36) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL668634 | 0.93 | ABCB1 (0.36) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL17416637 | 0.90 | PLK1 (0.39) | ALDH1A1NPC1MAPTRAB9AHSD17B10 | |
| SCHEMBL29685124 | 0.86 | ABCB1 (0.38) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL668095 | 0.86 | ABCB1 (0.38) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL2684734 | 0.86 | ABCB1 (0.38) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL668085 | 0.86 | ABCB1 (0.38) | ALDH1A1NPC1MAPTRAB9AABCB1 | |
| SCHEMBL29786240 | 0.86 | ABCB1 (0.38) | ALDH1A1NPC1MAPTRAB9AABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2463269-A1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | Intrexon Corporation (US) | 2012-06-13 | — | — | EP | disclosed |