Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9903405 | 1.00 | GPR35 (0.35) | GPR35SMN1; SMN2 | |
| SCHEMBL9903797 | 0.83 | BRD4 (0.36) | — | |
| SCHEMBL9903873 | 0.83 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL9903354 | 0.83 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11893788 | 0.83 | BRD4 (0.35) | — | |
| SCHEMBL9903582 | 0.80 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL9903657 | 0.80 | GLRA1 (0.36) | SMN1; SMN2 | |
| SCHEMBL9902728 | 0.80 | GLRA1 (0.36) | SMN1; SMN2 | |
| SCHEMBL9902897 | 0.78 | LMNA (0.31) | SMN1; SMN2 | |
| SCHEMBL9902894 | 0.78 | LMNA (0.31) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8916549-B2 | Thienooxazepine derivative | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2463290-B1 | THIENOOXAZEPINE DERIVATIVE | TAKEDA PHARMACEUTICAL (JP) | 2014-03-05 | — | — | EP | disclosed |
| EP-2463290-A1 | THIENOOXAZEPINE DERIVATIVE | Takeda Pharmaceutical Company Limited (JP) | 2012-06-13 | — | — | EP | disclosed |