Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746437 | 0.88 | PPARD (0.57) | PPARDMAPTPPARGPPARAKDM4E | |
| SCHEMBL1746440 | 0.88 | PPARD (0.57) | PPARDMAPTPPARGPPARAKDM4E | |
| SCHEMBL1746442 | 0.88 | PPARD (0.57) | PPARDMAPTPPARGPPARAKDM4E | |
| SCHEMBL1745153 | 0.85 | TSHR (0.49) | PPARDMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL1745152 | 0.85 | TSHR (0.49) | PPARDMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL1745154 | 0.85 | TSHR (0.49) | PPARDMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL22829501 | 0.83 | KDM4E (0.45) | PPARDNPC1RAB9APPARGPPARA | |
| SCHEMBL16553795 | 0.81 | PPARD (0.45) | PPARDNPC1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL9920812 | 0.79 | PPARD (0.62) | PPARDMAPTPPARGPPARAKDM4E | |
| SCHEMBL1744321 | 0.78 | PPARD (0.55) | PPARDPPARGPPARAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979311-B1 | PHENOXY ACETIC ACIDS AS PPAR DELTA ACTIVATORS | HIGH POINT PHARMACEUTICALS LLC (US) | 2012-06-13 | — | — | EP | claimed |