Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904223 | 0.93 | PTGES (0.45) | PTGES | |
| SCHEMBL9900181 | 0.86 | PTGES (0.45) | PTGES | |
| SCHEMBL9939982 | 0.85 | PTGES (0.44) | PTGES | |
| SCHEMBL9941975 | 0.84 | PTGES (0.46) | PTGES | |
| SCHEMBL9939937 | 0.81 | PTGES (0.53) | PTGES | |
| SCHEMBL9939942 | 0.81 | PTGES (0.59) | PTGES | |
| SCHEMBL9905788 | 0.81 | PTGES (0.47) | PTGES | |
| SCHEMBL9939848 | 0.81 | PTGES (0.52) | PTGES | |
| SCHEMBL9939940 | 0.80 | PTGES (0.49) | PTGES | |
| SCHEMBL9941998 | 0.80 | PTGES (0.51) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649052-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |