Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9904214 | 0.93 | PTGES (0.42) | PTGES | |
| SCHEMBL9900209 | 0.85 | PTGES (0.48) | PTGES | |
| SCHEMBL9905785 | 0.85 | PTGES (0.47) | PTGES | |
| SCHEMBL16181898 | 0.81 | PTGES (0.48) | PTGES | |
| SCHEMBL9904125 | 0.81 | PTGES (0.53) | PTGES | |
| SCHEMBL9939980 | 0.80 | PTGES (0.57) | PTGES | |
| SCHEMBL9905787 | 0.80 | PTGES (0.50) | PTGES | |
| SCHEMBL9939979 | 0.79 | PTGES (0.52) | PTGES | |
| SCHEMBL9900181 | 0.79 | PTGES (0.45) | PTGES | |
| SCHEMBL9939982 | 0.78 | PTGES (0.44) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2649052-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | Boehringer Ingelheim International GmbH (DE) | 2013-10-16 | — | — | EP | disclosed |
| WO-2012076672-A1 | 2 -AMINOBENZ IMIDAZOLE DERIVATIVES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | WO | disclosed |