Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 5/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | HTT | P42858 | 3/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CDK5 | Q00535 | 2/20 | 1.00 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 1.00 |
| ▸ | TP53 | P04637 | 1/20 | 1.00 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31060198 | 1.00 | PRKD1 (1.00) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL9904150 | 0.96 | PRKD1 (1.00) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL9920687 | 0.92 | PRKD1 (0.84) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL15471995 | 0.83 | ALDH1A1 (0.71) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL9920464 | 0.82 | PRKD1 (1.00) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL9904237 | 0.80 | ALDH1A1 (0.67) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL15465752 | 0.80 | ALDH1A1 (0.66) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL10401208 | 0.80 | LMNA (0.66) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL9920465 | 0.79 | ALDH1A1 (0.65) | PRKD1ALDH1A1HTTLMNACDK5 | |
| SCHEMBL9904284 | 0.78 | ALDH1A1 (0.64) | PRKD1ALDH1A1HTTLMNACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119464182-A | Compounds and methods for culturing and/or expanding hepatocytes | 南京昕瑞再生医药科技有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-118302516-A | Compounds and methods for hepatocyte expansion | 南京昕瑞再生医药科技有限公司 | 2024-07-05 | — | — | CN | claimed |
| WO-2023093807-A1 | COMPOUND AND METHOD FOR TREATING LIVER DISEASES | 南京昕瑞再生医药科技有限公司 | 2023-06-01 | — | — | WO | claimed |
| WO-2023093808-A1 | COMPOUND AND METHOD FOR HEPATOCYTE AMPLIFICATION | 南京昕瑞再生医药科技有限公司 | 2023-06-01 | — | — | WO | claimed |
| CN-109722411-B | Application method of micromolecules for promoting self-renewal state of embryonic stem cells | 安徽大学 | 2022-05-06 | — | — | CN | claimed |
| EP-4048809-B1 | SYSTEMS AND METHODS FOR PREDICTING THERAPEUTIC SENSITIVITY | TEMPUS AI INC (US) | 2026-05-27 | — | — | EP | disclosed |
| EP-4729940-A2 | LARGE SCALE ORGANOID ANALYSIS | Tempus AI, Inc. (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260024617-A1 | METHODS AND SYSTEMS FOR PERSONALIZED THERAPIES | SCIPHER MEDICINE CORP (US) | 2026-01-22 | — | — | US | disclosed |
| US-20260011445-A1 | SYSTEMS AND METHODS FOR PREDICTING THERAPEUTIC SENSITIVITY | TEMPUS AI INC (US) | 2026-01-08 | — | — | US | disclosed |
| EP-4070098-B1 | LARGE SCALE ORGANOID ANALYSIS | TEMPUS AI INC (US) | 2025-12-24 | — | — | EP | disclosed |
| US-12451250-B2 | Systems and methods for predicting therapeutic sensitivity | TEMPUS AI, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| US-20250285704-A1 | QUANTIFYING EFFECTS OF SEQUENCING VARIANCE ON CLASSIFICATION | ARES CAPITAL CORPORATION, AS COLLATERAL AGENT | 2025-09-11 | — | — | US | disclosed |
| EP-3194569-A1 | DIFFERENTIATION OF HEPATOCYTE-LIKE CELLS FROM STEM CELLS | Agency For Science, Technology And Research (SG) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016043666-A1 | DIFFERENTIATION OF HEPATOCYTE-LIKE CELLS FROM STEM CELLS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2016-03-24 | — | — | WO | disclosed |
| WO-2015193680-A1 | TREATMENT | IMPERIAL INNOVATIONS LIMITED (GB) | 2015-12-23 | — | — | WO | disclosed |
| US-20140045821-A1 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2014-02-13 | — | — | US | disclosed |
| US-20140045821-A1 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2014-02-13 | — | — | US | disclosed |
| US-20140045821-A1 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2014-02-13 | — | — | US | disclosed |
| WO-2012078859-A2 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012078859-A2 | PROTEIN KINASE D INHIBITORS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260011445-A1 | SYSTEMS AND METHODS FOR PREDICTING THERAPEUTIC SENSITIVITY | BRCA1, PARP2, PARP4 | PRKD1 108/4885ALDH1A1 606/4885HTT 3897/4885 |
| US-20140045821-A1 | PROTEIN KINASE D INHIBITORS | PRKCD, PRKD1, PRKD2 | PRKD1 2/4885ALDH1A1 4548/4885HTT 2479/4885 |
| US-20260024617-A1 | METHODS AND SYSTEMS FOR PERSONALIZED THERAPIES | SET, SSB, CNKSR1 | PRKD1 1955/4885ALDH1A1 3879/4885HTT 2738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.