Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 7/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TSSK1B | Q9BXA7 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12794452 | 0.74 | KDM4E (0.62) | KMT2AALDH1A1HPGDGAAKDM4E | |
| SCHEMBL30637053 | 0.74 | KDM4E (0.62) | KMT2AALDH1A1HPGDGAAKDM4E | |
| SCHEMBL9904546 | 0.69 | KDM4E (0.58) | KMT2AALDH1A1HPGDGAAKDM4E | |
| SCHEMBL19386336 | 0.69 | HRH4 (0.52) | KMT2AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL4548501 | 0.67 | — | — | |
| SCHEMBL4303506 | 0.67 | ALDH1A1 (0.54) | KMT2AALDH1A1HPGDGAAKDM4E | |
| SCHEMBL4308827 | 0.67 | CYP1A2 (0.52) | KMT2AALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL15647696 | 0.65 | PDE3B (0.42) | KMT2AMEN1CYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL4314822 | 0.65 | DAO (0.48) | KMT2AALDH1A1HPGDGAAKDM4E | |
| SCHEMBL9925837 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |