SCHEMBL9904673

SCHEMBL9904673

CC(C)c1nc2cscc2nc1-n1cncn1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24135612 0.69 CYP2A6 (0.36) ADORA2AADORA1
SCHEMBL9904722 0.68 KDM4E (0.35)
SCHEMBL9900096 0.67 POLB (0.46)
SCHEMBL3622108 0.65 CYP1A2 (0.36) ADORA2AADORA1
SCHEMBL9900932 0.65 CSNK1A1 (0.33)
SCHEMBL9900599 0.65
SCHEMBL9925837 0.64
SCHEMBL9901079 0.64 GLP1R (0.36)
SCHEMBL24135601 0.60 CYP2A6 (0.34) ADORA2AADORA1
SCHEMBL8669728 0.59 ALOX5AP (0.36) ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012076966-A1 SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS LUPIN LIMITED (IN) 2012-06-14 WO disclosed